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Compared to HGPS, the onset of Werner syndrome is slightly slower, in which the pathology accompanies with Werner syndrome resembles a premature aging

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[6] [7] The SYNERGY-NASH phase 2 trial has investigated histological outcomes in patients with steatohepatitis and fibrosis, with preliminary data suggesting that a proportion of participants achieved resolution of hepatic steatosis, defined as liver fat content below 5%